Use of Ibuprofen can cause many long-term side effects on kidney, like all non-steroidal anti-inflammatory drugs (NSAID) class. Read about Ibuprofen and several long term side effects of this pain reliever drug on kidney.
Ibuprofen is the most commonly used pain reliever drug which works by decreasing the prostaglandin secretion. On long term use, it can cause many side effects including kidney damage. Refer this article to know about the long term side effects of ibuprofen on the kidney.
Ibuprofen is an over the counter pain reliever drug which comes under the category of non-steroidal anti-inflammatory drugs (NSAIDs). The Food and Drug Administration (FDA) approved this drug as a safe non-steroidal anti-inflammatory in 1974. Primarily, it is used to treat mild to moderate pain such as headaches, muscle aches, backaches, dental pain, menstrual cramps, arthritis, and athletic injuries for the relief of everyday. Also, it is used to decrease fever and to relieve minor aches and pain due to common ailments and diseases like osteoarthritis and rheumatoid arthritis. Presently, ibuprofen is sold under the names Motrin, Advil, Medipren, Nuprin and others, which relieves pain and swelling (inflammation).
In the body, excessive prostaglandin secretion is responsible for pain, swelling, and fever. Ibuprofen is a generic drug which works by blocking the enzyme in body that involves in the production of prostaglandins. So, reducing the prostaglandin secretion helps to decrease pain, fever and inflammation. Like all non-steroidal anti-inflammatory drugs, ibuprofen use has also several potential side effects. As per FDA, it is safe to use but some mild side effects have been proven to exist after a year or long term use. Consult your doctor immediately, if any side effect takes place.
Long term side effects are very rare but ibuprofen can cause kidney disease particularly in at-risk patients as reported in the scientific literature. Ibuprofen mostly affects two organ systems of the body: the renal (kidneys) and gastrointestinal (GI) systems. Kidney damage is resulted from the chronic ingestion of NSAIDs and it is usually reversible in many cases. Sometimes, it may also occur as the result of short term usage (i.e. one or two doses). Diabetes and dehydration are contributing factors which raise the risk of renal toxicity.
Long Term Side Effects of Ibuprofen on Kidney:
Elder people or those individuals who have pre-existing kidney disease, heart or liver dysfunction, diuretic or ACE inhibitor users or impairment in kidney are at greatest risk for ibuprofen-induced renal side effects. Kidney damage and dysfunction is usually caused by long-term use of ibuprofen. Long-term use of non-steroidal anti-inflammatory, ibuprofen has resulted in renal papillary necrosis and other kidney impairment, as per the “PDR Guide to Drug Interactions, Side Effects, and Indications”.
A renal papillary necrosis takes place in some individuals on long term use of ibuprofen. In this condition, parts of kidney are responsible for concentrating the urine die. Aside from damage to the kidneys, it also alters the sodium and water balance which is regulated by the kidney, having profound consequences in hot training and racing environments.
* Acute Kidney Failure:
A single dose of ibuprofen is also responsible for sudden-onset acute kidney failure if the patient suffers from chronic kidney disease or lupus, or drinks a lot of alcohol. For acute renal failure due to ibuprofen, independent risk factors also include advanced age and childhood. Patients with reduced kidney function are not recommended to take ibuprofen, as warned by the National Kidney Foundation.
* Analgesic Nephropathy:
Long-term use of ibuprofen and other NSAIDs cause kidney damage called as analgesic nephropathy. Analgesic nephropathy takes place in approximately four out of 100,000 people, primarily from self-medication. The analgesic nephropathy risk is related with the duration of use. Patients who have taken six or more pills per day for more than three years are on greater risk for the analgesic nephropathy.
If analgesic nephropathy occurs, then it can result in permanent kidney damage. Further kidney damage can be prevented by treating the symptoms of existing damage such as hypertension and urine protein.
* Pre-term Babies:
Kidneys of premature babies are also affected by the effect of ibuprofen, according to the report from 2010 issue of “Pediatric Nephrology”. Studies have found that seven days of treatment with ibuprofen considerably reduces the filtration rate of blood in infant’s kidneys.
किन आज म यहाँ
मलाई त लाग्छ की किन हो किन
हजुरको इच्छा के छ मलाई दिन
तर पनि जे भय पनि उस्तै हो जिन्दाकी
टाढाको बसाइमा जे भय पनि हुदैन की
तर पनि यो मनले जसरी भय पनि
हजुरलाई सधै खोज्छ यो पापी पनि
सोचाई त हजार हजार आनि अरु
कसरी हुन्छ हुन्छ म भन्नु न बरु
तो सरिरको त के बयान गरु श्रिस्टीको पाटो
जती पल्टायो जति हेर्यो न थाक्ने न भारिने पोल्टो
जे भय पनि हजूर मेरी रानी कता हो कता
म त रुदै छू येस भूमिमा र म यहाँ यता
तो सरिरको त के बयान गरु श्रिस्टीको पाटो
जती पल्टायो जति हेर्यो न थाक्ने न भारिने पोल्टो
जे भय पनि हजूर मेरी रानी कता हो कता
म त रुदै छू येस भूमिमा र म यहाँ यता
Always Follow Your Dreams
There were once 2 brothers who lived on the 80th level. On coming home one day, they realized to their dismay that the lifts were not working and that they have to climb the stairs home.
After struggling to the 20th level, panting and tired, they decided to abandon their bags and come back for them the next day. They left their bags then and climbed on. When they have struggled to the 40th level, the younger brother started to grumble and both of them began to quarrel. They continued to climb the flights of steps, quarreling all the way to the 60th floor.
They then realized that they have only 20 levels more to climb and decided to stop quarreling and continue climbing in peace. They silently climbed on and reached their home at long last. Each stood calmly before the door and waited for the other to open the door. And they realized that the key was in their bags which was left on the 20th floor.
This story is reflecting on our life…many of us live under the expectations of our parents, teachers and friends when young. We seldom get to do the things that we really like and love and are under so much pressure and stress so that by the age of 20, we get tired and decided to dump this load.
Being free of the stress and pressure, we work enthusiastically and dream ambitious wishes. But by the time we reach 40 years old, we start to lose our vision and dreams. We began to feel unsatisfied and start to complain and criticize. We live life as a misery as we are never satisfied. Reaching 60, we realize that we have little left for complaining anymore, and we began to walk the final episode in peace and calmness.
We think that there is nothing left to disappoint us, only to realize that we could not rest in peace because we have an unfulfilled dream …… a dream we abandoned 60 years ago.
So what is your dream? Follow your dreams, so that you will not live with regrets.
After struggling to the 20th level, panting and tired, they decided to abandon their bags and come back for them the next day. They left their bags then and climbed on. When they have struggled to the 40th level, the younger brother started to grumble and both of them began to quarrel. They continued to climb the flights of steps, quarreling all the way to the 60th floor.
They then realized that they have only 20 levels more to climb and decided to stop quarreling and continue climbing in peace. They silently climbed on and reached their home at long last. Each stood calmly before the door and waited for the other to open the door. And they realized that the key was in their bags which was left on the 20th floor.
This story is reflecting on our life…many of us live under the expectations of our parents, teachers and friends when young. We seldom get to do the things that we really like and love and are under so much pressure and stress so that by the age of 20, we get tired and decided to dump this load.
Being free of the stress and pressure, we work enthusiastically and dream ambitious wishes. But by the time we reach 40 years old, we start to lose our vision and dreams. We began to feel unsatisfied and start to complain and criticize. We live life as a misery as we are never satisfied. Reaching 60, we realize that we have little left for complaining anymore, and we began to walk the final episode in peace and calmness.
We think that there is nothing left to disappoint us, only to realize that we could not rest in peace because we have an unfulfilled dream …… a dream we abandoned 60 years ago.
So what is your dream? Follow your dreams, so that you will not live with regrets.
Hang your troubles on the Tree!!
I hired a plumber to help me restore an old farmhouse, and after he had just finished a rough first day on the job, a flat tyre made him lose an hour of work, his electric drill quit and his ancient one-ton truck refused to start. While I drove him home, he sat in stony silence.
On arriving he invited me in to meet his family. As we walked towards the front door, he paused briefly at a tree, touching the tips of the tree. When opening the door he underwent an amazing transformation.
His tanned face was wreathed in smiles and he hugged his two small children and gave his wife a kiss. Afterward he walked me to the car. We passed the tree and my curiosity got the better of me. I asked him about what I had seen him do earlier.
Oh, that's my trouble tree," he replied. "I know I can't help having troubles on the job, but one thing's for sure, those troubles don't belong in the house with my wife and the children. So I just hang them up on the tree every night when I come home and ask God to take care of them. Then in the morning I pick them up again. "Funny thing is," he smiled, "when I come out in the morning to pick them up, there aren't nearly as many as I remember hanging up the night before."
On arriving he invited me in to meet his family. As we walked towards the front door, he paused briefly at a tree, touching the tips of the tree. When opening the door he underwent an amazing transformation.
His tanned face was wreathed in smiles and he hugged his two small children and gave his wife a kiss. Afterward he walked me to the car. We passed the tree and my curiosity got the better of me. I asked him about what I had seen him do earlier.
Oh, that's my trouble tree," he replied. "I know I can't help having troubles on the job, but one thing's for sure, those troubles don't belong in the house with my wife and the children. So I just hang them up on the tree every night when I come home and ask God to take care of them. Then in the morning I pick them up again. "Funny thing is," he smiled, "when I come out in the morning to pick them up, there aren't nearly as many as I remember hanging up the night before."
Deciding On Divorce
Deciding on divorce is a big decision. You should understand that you aren't a bad person just because you think you want a divorce.
Your spouse is not automatically a bad person because he/she may be causing you to feel this way (or so you may think), you're just people, plain and simple.
The Mindset You Need To Make This Difficult Decision You're reading this for a reason...because you have been thinking about divorce for one reason or another. Being in "limbo" is a horrible feeling because you can't really get rooted if you are in limbo...all you know is that you aren't happy and don't know what to do.
You may feel stuck in a rut or feel like you are wandering aimlessly. Whatever the case, not being certain of what will happen can be tough to swallow and only contributes to your being unhappy. Another reason that this is usually a tumultuous and arduous time for people who are in this stage of life because it usually involves self reflection and a heightened awareness that may never have been reached before in your life.
This can be most difficult and scary, but I assure you it is healthy in the long run. When doing this "inward reflection", you may find out some things about yourself that you may not like. You may recall some things you had forgotten. You may realize that this isn't all your fault or you may realize that you had a hand in leading yourself here too. Whatever happens from here on in, your mindset has to be conducive to being brutally honest to yourself.
Since this can be a gut-wrenching time in your life, you absolutely must realize that one serious danger you face is making the mistake of not being fully aware that people don't make clear decisions during heightened emotional times. You must remember that emotion clouds judgment and bad decisions are made when the wrong side of your brain produces something by using emotion rather than intellect.
This cannot be stressed enough...when making any decision or thinking deeply about a concept, make certain that you are logical and impartial to the best of your ability. You must be comfortable with finding flaws within yourself and realizing that those are flaws that you agree with. You must be ready to admit self guilt and self fault, or this won't work.
Your spouse is not automatically a bad person because he/she may be causing you to feel this way (or so you may think), you're just people, plain and simple.
The Mindset You Need To Make This Difficult Decision You're reading this for a reason...because you have been thinking about divorce for one reason or another. Being in "limbo" is a horrible feeling because you can't really get rooted if you are in limbo...all you know is that you aren't happy and don't know what to do.
You may feel stuck in a rut or feel like you are wandering aimlessly. Whatever the case, not being certain of what will happen can be tough to swallow and only contributes to your being unhappy. Another reason that this is usually a tumultuous and arduous time for people who are in this stage of life because it usually involves self reflection and a heightened awareness that may never have been reached before in your life.
This can be most difficult and scary, but I assure you it is healthy in the long run. When doing this "inward reflection", you may find out some things about yourself that you may not like. You may recall some things you had forgotten. You may realize that this isn't all your fault or you may realize that you had a hand in leading yourself here too. Whatever happens from here on in, your mindset has to be conducive to being brutally honest to yourself.
Since this can be a gut-wrenching time in your life, you absolutely must realize that one serious danger you face is making the mistake of not being fully aware that people don't make clear decisions during heightened emotional times. You must remember that emotion clouds judgment and bad decisions are made when the wrong side of your brain produces something by using emotion rather than intellect.
This cannot be stressed enough...when making any decision or thinking deeply about a concept, make certain that you are logical and impartial to the best of your ability. You must be comfortable with finding flaws within yourself and realizing that those are flaws that you agree with. You must be ready to admit self guilt and self fault, or this won't work.
The Spiritual Race
Life is a mix of pain and of sorrow,
There seems to be no bright tomorrows...
Yet today the sun may shine awhile,
And encourage another cheerful smile.
We can thank God for His mercy and love,
Knowing He sees from His throne above...
He uses each twist of anxiety and pain,
For our own good, for our own gain.
But when our patience is tried too long,
We forget the words to our 'thankful' song.
I asked God to open my blind eyes to see,
All His warm love that encircles me.
And to open my ears to hear a bluebird sing,
Because His special gifts mean everything.
There's an answer for all sadness and gloom...
Could it be the fragrance of a red rose in bloom?
Or the twinkling stars that shine in the night?
Or the pale moon's own pure light?
Or sunbeams dancing through the rain,
Helping us to smile instead of complain?
How amazing is our Lord's mercy and grace,
As we run to win this spiritual race...
"Believe in the Lord because He is good."
Only then can we live the way we should.
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